Enantioselective Organocatalytic Four-Atom Ring Expansion of Cyclobutanones: Synthesis of Benzazocinones.
DOI Number:
10.1002/ange.201810184
Reaction Category:
MOP ID:
MOP_0000561
Educt:
tert-butyl (E)-(2-(2-nitrovinyl)phenyl)carbamate, ethyl 4-(2-oxocyclobutane-1-carboxamido)benzoate
Product:
tert-butyl (5S,6R)-5-((4-(ethoxycarbonyl)phenyl)carbamoyl)-6-(nitromethyl)-2-oxo-3,4,5,6-tetrahydrobenzo[b]azocine-1(2H)-carboxylate
Catalyst:
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione
Cas No:
1256245-82-5
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5