Bifunctional squaramide catalysts with the same absolute chirality for the diastereodivergent access to densely functionalised cyclohexanes through enantioselective domino reactions. Synthesis and mechanistic studies.
DOI Number:
10.1002/adsc.201400502
Reaction Category:
RXNO ID:
RXNO_0000086
Educt:
substituted 2-nitro-5-oxopentanoate, (E)-1-nitroalk-1-enes
Product:
densely functionalised cyclohexanes
Catalyst:
3-((3,5-bis(trifluoromethyl)benzyl)amino)-4-(((R)-(6-methoxyquinolin-4-yl) ((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione
Cas No:
1073917-09-5
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2