Asymmetric 5-endo chloroetherification of homoallylic alcohols toward the synthesis of chiral β-chlorotetrahydrofurans.

DOI Number:

10.1039/C2CC38436A
Link to literature

Reaction Category:

Chlorination | Cyclization

MOP ID:

MOP_0000551

Educt:

substituted (E)-4-phenylbut-3-en-1-ol, N-chlorsuccinimid

Product:

substituted (2R,3S)-3-chloro-2-phenyltetrahydrofuran

Catalyst:

9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]- (9S)-Cinchonanium bromide

Cas No:

95088-20-3

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5