Asymmetric dearomative cascade multiple functionalizations of activated N-alkylpyridinium and N-alkylquinolinium salts.

DOI Number:

10.1021/acs.orglett.0c02828

Reaction Category:

Educt:

N-alkylpyridinium salts, (E)-4-(2-hydroxyphenyl)but-3-en-2-one, (E)-4-(2-(phenylamino)phenyl)but-3-en-2-one

Product:

substituted (3aR,3a1S,6aR,11bR)-6-benzyl-3,3a,3a1,6,6a,11b-hexahydrochromeno[4,3,2-ij]isoquinolin-2(1H)-one

Catalyst:

3-methyl-D-Valine (9S)-6′-methoxycinchonan-9-yl ester

Cas No:

2515441-80-0

Cas No:

130-95-0