Cooperative catalysis-enabled C–N bond cleavage of biaryl lactams with activated isocyanides.

DOI Number:

10.1039/d2cc01625g
Link to literature

Reaction Category:

C-N bond cleavage | Further reactions

Educt:

1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, 3-oxo-3-(pyrrolidin-1-yl)propanenitrile

Product:

N-(3,5-dimethyl-2-(2-(4-(pyrrolidine-1-carbonyl)oxazol-5-yl)naphthalen-1-yl)phenyl)-4-methylbenzenesulfonamide

Catalyst:

silver carbonate, 3-[(1,1-Dimethylethyl)amino]-4-[[(8α,9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1904591-09-8

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0