Catalytic chemo-, regio-, diastereo-, and enantioselective bromochlorination of unsaturated systems enabled by Lewis base-controlled chloride release.

DOI Number:

10.1021/jacs.2c04588

Reaction Category:

Educt:

(E)-chalcone, sulfurous dichloride, N-bromsuccinimid

Product:

(2R,3S)-2-bromo-3-chloro-1,3-diphenylpropan-1-one

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7