Silicon-Based Lewis Acid Assisted Cinchona Alkaloid Catalysis: Highly Enantioselective Aza-Michael Reaction under Solvent-Free Conditions

DOI Number:

10.1021/ol202803b

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

substituted (E)-chalcone, substituted aniline

Product:

substituted aromatic beta-amino ketones

Catalyst:

trimethylsilylhalides, Cinchonine Base

Cas No:

118-10-5

Cas No:

118-10-5