Squaramide-catalysed asymmetric cascade aza-Michael/Michael addition reaction for the synthesis of chiral trisubstituted pyrrolidines.

DOI Number:

10.1039/C5OB01749A

Reaction Category:

Educt:

nitroalkenes, tosyl protected δ‐amino-α,β-unsaturated ketones

Product:

trisubstituted pyrrolidines

Catalyst:

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1352957-59-5

Cas No:

522-66-7