Stereoselective Synthesis of Chiral Hydrophenanthridines via a One-Pot Stepwise Aza-Michael/Michael/Michael Process.

DOI Number:

10.1021/acs.orglett.2c01866
Link to literature

Reaction Category:

Aza-Michael | Michael Addition

Educt:

4-methyl-N-(2-((1E,4E)-3-oxo-5-phenylpenta-1,4-dien-1-yl)phenyl)benzenesulfonamide, (E)-(2-nitrovinyl)benzene

Product:

Hydrophenanthridines

Catalyst:

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-79-0

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2