Asymmetric synthesis of functionalized tetrasubstituted α-aminophosphonates through enantioselective aza-Henry reaction of phosphorylated ketimines.
DOI Number:
10.1021/jo502233m
Reaction Category:
RXNO ID:
RXNO_0000235
Educt:
disubstituted (E)-(phenyl(tosylimino)methyl)phosphonate, nitromethane
Product:
disubstituted (R)-(1-((4-methylphenyl)sulfonamido)-2-nitro-1-phenylethyl)phosphonate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9S)-cinchonan-9-ylthiourea
Cas No:
851477-18-4
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5