Highly Enantioselective Synthesis of (R)-α-Alkylserines via Phase-Transfer Catalytic Alkylation of o-Biphenyl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester Using Cinchona-Derived Catalysts.

DOI Number:

10.1021/ol050228x

Reaction Category:

MOP ID:

MOP_0000369

Educt:

o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 3-bromoprop-1-ene, (bromomethyl)benzene

Product:

substituited o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester

Catalyst:

O-Allyl-1-(anthracen-9-ylmethyl)-cinchonidinium Bromide

Cas No:

200132-54-3

Associated Product from Buchler GmbH:

O-Allyl-1-(anthracen-9-ylmethyl)-cinchonidinium Bromide

Cas No:

200132-54-3