Enantioselective Alkylation of β-Keto Esters by Phase-Transfer Catalysis Using Chiral Quaternary Ammonium Salts.

DOI Number:

10.1021/jo0401772
Link to literature

Reaction Category:

Alkylation | alpha-Alkylation

MOP ID:

MOP_0000369

Educt:

methyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate, 1-(bromomethyl)-4-nitrobenzene

Product:

methyl (S)-2-(4-nitrobenzyl)-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate

Catalyst:

(9S)-1-[[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]methyl]-9-(2-propen-1-yloxy)-cinchonanium bromide

Cas No:

405506-33-4

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5