A novel enantioselective alkylation and its application to the synthesis of an anticancer agent.

DOI Number:

10.1021/jo034380t

Reaction Category:

MOP ID:

MOP_0000369

Educt:

3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, tert-butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate

Product:

(R)-3,10-dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Catalyst:

Quinine Base

Cas No:

130-95-0

Cas No:

130-95-0