Asymmetric Total Synthesis of Leptosphin C.

DOI Number:

10.1021/acs.orglett.5c03236
Link to literature

Reaction Category:

Aldol | Hajos–Parrish–Eder–Sauer–Wiechert reaction

RXNO ID:

RXNO_0000016

Educt:

TMS-protected 2-(prop-2-yn-1-yl)cyclopentane-1,3-dione, (E)-pent-3-en-2-one

Product:

bicylce

Catalyst:

N-[(1S,2S)-2-aminocyclohexyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-thiourea

Cas No:

1240123-02-7

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2