Asymmetric Synthesis of Adjacent Tri- and Tetrasubstituted Carbon Stereocenters: Organocatalytic Aldol Reaction of an Hydantoin Surrogate with Azaarene 2-Carbaldehydes.

DOI Number:

10.1002/chem.201902817

Reaction Category:

Educt:

substituted 2-(benzylthio)-3,5-dihydro-4H-imidazol-4-one, pyridine 2-carbaldehyde N-oxides

Product:

substituted 2-((1S)-(2-(benzylthio)-5-oxo-4,5-dihydro-1H-imidazol-4-yl)(hydroxy)methyl)pyridine 1-oxide

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-benzamide

Cas No:

2071700-89-3

Cas No:

130-95-0