Bifunctional Brønsted Base Catalyzes Direct Asymmetric Aldol Reaction of a-Keto Amides.

DOI Number:

10.1002/anie.201510482

Reaction Category:

RXNO ID:

RXNO_0000016

Educt:

N,N-dibenzyl-3-(naphthalen-2-ylmethoxy)-2-oxopropanamide, 3-phenylpropanal

Product:

(3S,4R)-N,N-dibenzyl-4-hydroxy-3-(naphthalen-2-ylmethoxy)-2-oxo-6-phenylhexanamide

Catalyst:

Phenylmethyl N-[(1S)-1-[[[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate

Cas No:

1875034-25-5

Cas No:

522-66-7