Highly Enantioselective and Efficient Organocatalytic Aldol Reaction of Acetone and β, γ-Unsaturated α-Keto Ester.

DOI Number:

10.1021/ol102254q
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

methyl (E)-4-(3-nitrophenyl)-2-oxobut-3-enoate, acetone

Product:

methyl (S,E)-2-hydroxy-2-(3-nitrostyryl)-4-oxopentanoate

Catalyst:

4-nitrobenzoic acid, (9R)-Cinchonan-9-amine

Cas No:

168960-96-1

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5