Direct catalytic asymmetric synthesis of oxindole-derived δ-hydroxy-β-ketoesters by Aldol reactions.
DOI Number:
10.1021/acs.orglett.9b03527
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
5-methoxyindoline-2,3-dione, methyl 3-oxobutanoate
Product:
methyl (R)-4-(3-hydroxy-5-methoxy-2-oxoindolin-3-yl)-3-oxobutanoate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8