Organocatalytic decarboxylative aldol reaction of β-ketoacids with α-ketophosphonates en route to the enantioselective synthesis of tertiary α-hydroxyphosphonates.

DOI Number:

10.1039/C7OB00796E
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

3-oxocarboxylic acids, α-ketophosphonates

Product:

tertiary α-hydroxyphosphonates

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea

Cas No:

1326239-56-8

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2