Asymmetric synthesis of vicinally bis(trifluoromethyl)-substituted 3,30-pyrrolidinyl spirooxindoles via organocatalytic 1,3-dipolar cycloaddition reactions.
DOI Number:
10.1055/s-0037-1612089
Reaction Category:
MOP ID:
MOP_0000715
Educt:
N-2,2,2-trifluoroethylisatin ketimines, 3-(trifluoroethylidene)oxindoles
Product:
vicinally bis(trifluoromethyl)-substituted 3,30-pyrrolidinyl spirooxindoles
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0