Asymmetric synthesis of vicinally bis(trifluoromethyl)-substituted 3,30-pyrrolidinyl spirooxindoles via organocatalytic 1,3-dipolar cycloaddition reactions.

DOI Number:

10.1055/s-0037-1612089

Reaction Category:

Educt:

N-2,2,2-trifluoroethylisatin ketimines, 3-(trifluoroethylidene)oxindoles

Product:

vicinally bis(trifluoromethyl)-substituted 3,30-pyrrolidinyl spirooxindoles

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0