Mannich reaction, N-protected phenylmethanimine, 3-methylindolin-2-one, N-protected (R)-3-((R)-amino(phenyl)methyl)-3-methylindolin-2-one, (8α,9R)-9-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-cinchonan-6′-ol, Cupreine Derivative by werner@buchler-gmbh.com | Apr 24, 2026
Lactonization, 2-keto succinates, formaldehyde, γ-butyrolactones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxy-2′-phenylcinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinine Derivative by werner@buchler-gmbh.com | Apr 7, 2026
Michael Addition, azlactones, α,β‐unsaturated trichloromethyl ketones, α,α-disubstituted α-amino acid derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivatives by werner@buchler-gmbh.com | Jan 13, 2026
Peroxidation, α,β-unsaturated nitroalkenes, (1-hydroperoxy-1-methoxyethyl)benzene, 1-substituted 1-hydroperoxy-2-nitroethane, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative by werner@buchler-gmbh.com | Sep 15, 2025
Desymmetrization, hexahydroisobenzofuran-1,3-dione, methanol, (1S,2R)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative by werner@buchler-gmbh.com | Sep 11, 2025