Non-enzymatic catalytic asymmetric cyanation of acylsilanes.

DOI Number:

10.1038/s42004-022-00662-y
Link to literature

Reaction Category:

Cyanation

MOP ID:

MOP_0000597

Educt:

1-(tert-butyldimethylsilyl)-4-phenylbutan-1-one, trimethylsilanecarbonitrile

Product:

(S)-2-(tert-butyldimethylsilyl)-2-hydroxy-5-phenylpentanenitrile

Catalyst:

1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]oxy]-9,10-Anthracenedione

Cas No:

176097-24-8

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7