An enantioselective synthesis of (+)-polyoxamic acid via phase-transfer catalytic conjugate addition and asymmetric dihydroxylation.

DOI Number:

10.1021/jo102272h
Link to literature

Reaction Category:

Alkylation | alpha-Alkylation

MOP ID:

MOP_0000369

Educt:

tert-butyl 2-((diphenylmethylene)amino)acetate, ethyl 2-(phenylselanyl)acrylate

Product:

1-(tert-butyl) 5-ethyl (2S)-2-((diphenylmethylene)amino)-4-(phenylselanyl)pentanedioate

Catalyst:

(8α,9R)-1-(9-anthracenylmethyl)-10,11-dihydro- 9-(2-propen-1-yloxy)-Cinchonanium bromide

Cas No:

550358-96-8

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3