Asymmetric synthesis of 3,4‐dihydrocoumarins bearing an α,α‐disubstituted amino acid moiety.

DOI Number:

10.1002/adsc.201500598
Link to literature

Reaction Category:

Cascade reaction

Educt:

4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one

Product:

3,4‐dihydrocoumarins

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7