Catalytic Enantioselective Chlorofunctionalizations of N-Substituted Amides Using In Situ Generated HOCl as Hydrogen Bond Source.

DOI Number:

10.1021/jacs.5c01224
Link to literature

Reaction Category:

Chlorination | Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000551

Educt:

N-substituted amides, 1,3-dichlor-5,5-dimethylhydantoin

Product:

substituted 5-(chloromethyl)oxazolidin-2-one, substituted 3-amino-2-(chloromethyl)propanoate

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7