Synthesis of kurasoin B using phase-transfer-catalyzed acylimidazole alkylation.

DOI Number:

10.1055/s-0028-1087809
Link to literature

Reaction Category:

Alkylation | alpha-Alkylation

MOP ID:

MOP_0000369

Educt:

2-(benzyloxy)-1-(1-methyl-1H-imidazol-2-yl)ethan-1-one, tert-butyl 3-(bromomethyl)-1H-indole-1-carboxylate

Product:

tert-butyl (S)-3-(2-(benzyloxy)-3-(1-methyl-1H-imidazol-2-yl)-3-oxopropyl)-1H-indole-1-carboxylate

Catalyst:

(8α,9R)-(8′′α,9′′R)-1,1′′-[2,7-naphthalenediylbis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium bromide

Cas No:

480427-57-4

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3