Phase-transfer-catalyzed asymmetric acylimidazole alkylation.

DOI Number:

10.1021/ol702197r
Link to literature

Reaction Category:

Alkylation | alpha-Alkylation

MOP ID:

MOP_0000369

Educt:

1-(1-methyl-1H-imidazol-2-yl)-2-(naphthalen-2-ylmethoxy)ethan-1-one, 2-(bromomethyl)naphthalene

Product:

(S)-1-(1-methyl-1H-imidazol-2-yl)-3-(naphthalen-2-yl)-2-(naphthalen-2-ylmethoxy)propan-1-one

Catalyst:

(8α,9R)-(8′′α,9′′R)-1,1′′-[2,7-naphthalenediylbis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium bromide

Cas No:

480427-57-4

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3