Enantioselective Addition of Thiols to Acyclic Ketiminoesters Using Cinchona Alkaloid Amide/Zinc (II) Catalysts.

DOI Number:

10.1002/adsc.202400674
Link to literature

Reaction Category:

Further reactions | Thiolation

Educt:

N-protected ethyl 2-imino-4-phenylbut-3-ynoate, 3-((trimethylsilyl)oxy)propane-1-thiol

Product:

N-protected ethyl (R)-2-amino-2-((3-hydroxypropyl)thio)-4-phenylbut-3-ynoate

Catalyst:

diethylzinc, N-[(8α,9S)-10,11-dihydrocinchonan-9-yl]-2-pyridinecarboxamide

Cas No:

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3