Organocatalytic atroposelective construction of axially chiral N,N- and N,S-1,2-azoles through novel ring formation approach.

DOI Number:

10.1038/s41467-022-29557-1
Link to literature

Reaction Category:

Atropisomer synthesis

Educt:

substituted 1-(3-hydrazineylideneprop-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide

Product:

atropisomeric pyrazoles

Catalyst:

(2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide

Cas No:

1509940-71-9

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0