A vinylogous Michael addition-triggered quadruple cascade reaction for the enantioselective generation of multiple quaternary stereocenters.

DOI Number:

10.1039/C8CC09219B
Link to literature

Reaction Category:

Cascade reaction

Educt:

2-(1-(4-bromophenyl)-3,3,3-trifluoro-2-oxopropylidene)-1H-indene-1,3(2H)-dione, tert-butyl (E)-2-oxo-3-(1-phenylethylidene)indoline-1-carboxylate

Product:

multiple quaternary stereocenters

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7