Asymmetric Mannich Reaction of Aryl Methyl Ketones with Cyclic Imines Benzo [e][1,2,3] oxathiazine 2,2‐Dioxides Catalyzed by Cinchona Alkaloid‐based Primary Amines.

DOI Number:

10.1002/asia.201601149
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

benzo[e][1,2,3]oxathiazine 2,2-dioxide, acetophenone

Product:

(S)-2-(2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-1-phenylethan-1-one

Catalyst:

(8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0