Syn-selective nitro-Michael addition of furanones to β,β-disubstituted nitroalkenes catalyzed by epi-quinine derivatives.
DOI Number:
10.1016/j.tetlet.2016.05.093
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
ethyl (Z)-3-nitro-2-(p-tolyl)acrylate, 5-isobutylfuran-2(3H)-one
Product:
ethyl (R)-2-((R)-2-isobutyl-5-oxo-2,5-dihydrofuran-2-yl)-3-nitro-2-(p-tolyl)propanoate
Catalyst:
(8α,9S)-9-[[2,4,6-Tris(1-methylethyl)phenyl]methoxy]cinchonan-6′-ol
Cas No:
1863900-12-2
Associated Product from Buchler GmbH:
Cupreine Base
Cas No:
524-63-0