Asymmetric synthesis of Rauhut–Currier-type esters via Mukaiyama–Michael reaction to acylphosphonates under bifunctional catalysis.

DOI Number:

10.1039/C8CC07561A
Link to literature

Reaction Category:

Further reactions | Michael | Michael Addition | Mukaiyama-Michael

RXNO ID:

RXNO_0000009

Educt:

substituted (E)-(buta-1,3-dien-1-yloxy)trimethylsilane, substituted diisopropyl acryloylphosphonate

Product:

substituted benzyl (E)-4-formylhex-4-enoate

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7