Organocatalytic asymmetric synthesis of trifluoromethyl-substituted diarylpyrrolines: enantioselective conjugate cyanation of β-aryl-β-trifluoromethyl-disubstituted enones.
DOI Number:
10.1002/anie.201201278
Reaction Category:
MOP ID:
MOP_0000597
Educt:
β-aryl-β-trifluoromethyl-disubstituted enones, 2-hydroxy-2-methylpropanenitrile
Product:
substituted 4-oxo-2-(trifluoromethyl)butanenitrile
Catalyst:
(9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide
Cas No:
1380297-63-1
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2