Organocatalytic asymmetric synthesis of trifluoromethyl-substituted diarylpyrrolines: enantioselective conjugate cyanation of β-aryl-β-trifluoromethyl-disubstituted enones.

DOI Number:

10.1002/anie.201201278

Reaction Category:

MOP ID:

MOP_0000597

Educt:

β-aryl-β-trifluoromethyl-disubstituted enones, 2-hydroxy-2-methylpropanenitrile

Product:

substituted 4-oxo-2-(trifluoromethyl)butanenitrile

Catalyst:

(9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide

Cas No:

1380297-63-1

Cas No:

56-54-2