Organocatalyzed enantioselective conjugated addition of sodium bisulfite to β-trifluoromethyl-α,β-unsaturated ketones.

DOI Number:

10.1021/acs.joc.8b00171
Link to literature

Reaction Category:

Addition

Educt:

β-trifluoromethyl-α,β-unsaturated ketones, sodium bisulfite

Product:

(R)-β-trifluoromethyl-β-sulfonic acid ketones

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-86-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2